科研成果
文章
Xuefeng Lu, Harmit Vora, Chaitan Khosla*. Overproduction of free fatty acids in E. coli: implications for biodiesel production. Metabolic Engineering. 2008, 10(6):333-339. doi:10.1016/j.ymben.2008.08.006
Rui Wu, Jian Cao, Xuefeng Lu, Albert S. Reger, Andrew. M. Gulick, Debra Dunaway-Mariano*. Mechanism of 4-chlorobenzoate: Coenzyme a ligase catalysi., Biochemistry. 2008. 47(31):8026-8039. doi:10.1021/bi800698m
Ling Li, Zhimin Li, Danqi Chen, Xuefeng Lu, Xiaohua Feng, Elizabeth C. Wright, Nathan O. Solberg, Debra Dunaway-Mariano*, Patrick S. Mariano*. Inactivation of microbial arginine deiminases by L-canavanine. Journal of the American Chemical Society. 2008. 130(6):1918-1931. doi:10.1021/ja0760877
Xuefeng Lu, Ling Li, Rui Wu, Xiaohua Feng, Zhimin Li, Heyi Yang, Canhui Wang, Hua Guo, Andrey Galkin, Osnat Herzberg, Patrick. S. Mariano, Brian M. Martin, Debra Dunaway-Mariano*. Kinetic analysis of Pseudomonas aeruginosa arginine deiminase mutants and alternate substrates provides insight into structural determinants of function. Biochemistry. 2006. 45(4):1162-1172. doi:10.1021/bi051591e
Jingbo Wu, Dingguo Xu, Xuefeng Lu, Canhui Wang, Hua Guo*, Debra Dunaway-Mariano*. ontributions of long-range electrostatic interactions to 4-chlorobenzoyl-CoA dehalogenase catalysis: a combined theoretical and experimental study. Biochemistry. 2005. 45(1):102-112. doi:10.1021/bi051477w
Xuefeng Lu, Ling Li, Xiaohua Feng, Yan Wu, Debra Dunaway-Mariano, John R. Engen, Patrick S. Mariano*. L-canavanine is a time-controlled mechanism-based inhibitor of Pseudomonas aeruginosa arginine deiminase. Journal of the American Chemical Society. 2005. 127(47):16412-16413. doi:10.1021/ja056226p 
Andrey Galkin, Xuefeng Lu, Debra Dunaway-Mariano, Osnat Herzberg*. Crystal structures representing the michaelis complex and the thiouronium reaction intermediate of Pseudomonas aeruginosa arginine deiminase. Journal of Biological Chemistry. 2005. 280(40):34080-34087. doi:10.1074/jbc.M505471200
Andrew M. Gulick*, Xuefeng Lu, Debra Dunaway-Mariano. Crystal structure of 4-chlorobenzoate: CoA ligase/synthetase in the unliganded and aryl substrate-bound states. Biochemistry. 2004. 43(27):8670-8679. doi:10.1021/bi049384m
Xuefeng Lu, Andrey Galkin, Osnat Herzberg, Debra Dunaway-Mariano*. Arginine deiminase uses an active-site cysteine in nucleophilic catalysis of L-arginine hydrolysis. Journal of the American Chemical Society. 2004. 126(17):5374-5375. doi:10.1021/ja049543p
Jian Dong, Xuefeng Lu, Yansheng Wei, Lusong Luo, Debra Dunaway-Mariano*, Paul R. Carey*. The strength of dehalogenase-substrate hydrogen bonding correlates with the rate of Meisenheimer intermediate formation. Biochemistry. 2003. 42(31):9482-9490. doi:10.1021/bi0347656