Leaders of Research Groups
Prof. Dr. HUANG Xuenian


Professor,Vice director of Center, Leader of Filamentous fungi Synthetic Biotechnology Group

2020-present, Professor,

Qingdao Institute of Bioenergy and Bioprocess Technology CAS;

2015-2020, Associate professor,

Qingdao Institute of Bioenergy and Bioprocess Technology CAS;

2012-2015, Assistant professor,

Qingdao Institute of Bioenergy and Bioprocess Technology CAS;

2010-2012, Research assistant,

Qingdao Institute of Bioenergy and Bioprocess Technology CAS;

Research Interests:

Synthetic biology of filamentous fungi, including genome mining of fungal natural products, metabolic engineering of industrial strains for the efficient production of important pharmaceutical and bio-based chemicals.

1、Xuenian Huang, Ping Men, Shen Tang, Xuefeng Lu*, Aspergillus terreus as an industrial filamentous fungus for pharmaceutical biotechnology, Current Opinion in Biotechnology, 2021, 69:273-280

2、Xuenian Huang#, Wei Zhang#, Shen Tang#, Suhui Wei, Xuefeng Lu*, Collaborative biosynthesis of a class of bioactive azaphilones by two separate gene clusters containing four PKS/NRPSs with transcriptional crosstalk in fungi, Angewandte Chemie Int Ed, 2020, 2020, 132: 4379-4383

3、Shen Tang#, Wei Zhang#, Zhimin Li, Hongcheng Li, Ce Geng, Xuenian Huang*, Xuefeng Lu*, Discovery and characterization of a PKS/NRPSHybrid in Aspergillus terreus by genome mining, Journal of Natural Products, 83: 473-480

4、Xuenian Huang, Shen Tang, Linghui Zheng, Yun Teng, Yong Yang, Jinwei Zhu, Xuefeng Lu*, (2019) Construction of an efficient and robust Aspergillus terreus cell factory for monacolin J production. ACS Synthetic Biology, 8:818-825

5、Xuenian Huang, Yajing Liang, Yong Yang, Xuefeng Lu*, (2017) Single-step production of the simvastatin precursor monacolin J by engineering of an industrial strain of Aspergillus terreus, Metabolic Engineering, 42: 109-114


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