Professor

Professor, Structure, Function, and Molecular mechanism study of proteins

Education Experience

2005.09-2009.07   Jilin University, Bachelor

2011.09-2016.07   Shanghai Institute of Materia Medica, CAS, Ph.D

Career Experience

2009.08-2010.06   Zhejiang Hisun Pharmaceutical Co., Ltd.

2010.07-2011.08   ACON Biotech (Hangzhou) Co., Ltd.

2016.07-2018.08   Shanghai Institute of Materia Medica, CAS, Post-doctor

2018.09-2021.03   Shanghai Institute of Materia Medica, CAS, Associate Professor

2021.04-2022.04   Shandong University, Professor

2022.05-Present   Qingdao Institute of Bioenergy and Bioprocess Technology, CAS, Professor

Selected publications:

1. Zhehua Shao#…Songmin Ying*, Honglei Ma*, and Yan Zhang*, Huahao Shen*(2022). Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3. Cell discovery, (2022) 8:44

2. Zhaotong Cong#, Li-Nan Chen#, Honglei Ma#, Qingtong Zhou#… Dehua Yang*, H. Eric Xu*, Yan Zhang*&Ming-Wei Wang*(2021). Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor. Nature. Communications. 12(3763)

3. Honglei Ma#,…Daopeng Yuan* & H. Eric Xu*(2020）. Structural insights into the activation of GLP-1R by a small molecule agonist. Cell Research. 0:1–3

4. Honglei Ma* …H. Eric Xu*, Jiayang Li* and Karsten Melcher*(2017). A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex. Science Advances. 2017.6.01,3(6)

5. Jiyuan Ke#, Honglei Ma#…H Eric Xu* and Karsten Melcher* (2015). Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors. Science Advances. 2015.7.01,1(6)