从事微生物分子生理学与合成生物学方向的研究，基本科研思路是通过新方法、新策略的开发应用来认识微生物细胞在胁迫应对和生物合成过程中的分子生理学机制，优化菌株生理和代谢功能，提高细胞工厂在生物炼制和光合生物制造过程中的整体效能。入选中国科学院青年创新促进会、研究所“清源学者-青年人才”计划、中科院特聘研究骨干、山东省人才计划。
2004/09-2008/06，山东大学生命科学学院，生物技术专业，获理学学士学位
2008/09-2014/06，中国科学院微生物研究所，微生物学专业，获理学博士学位
2014/07-2016/06，中国科学院青岛生物能源与过程研究所，博士后
2016/07-2016/12，中国科学院青岛生物能源与过程研究所，助理研究员
2016/12-2021/12，中国科学院青岛生物能源与过程研究所，副研究员
2021/12-至今，中国科学院青岛生物能源与过程研究所，研究员
2020/08-至今，中国科学院青岛生物能源与过程研究所，微生物制造工程中心副主任、蓝细菌合成生物技术研究组组长
社会任职情况:
担任GCB Bioenergy期刊编委、Frontiers in Microbiology及Frontiers in Bioengineering and Biotechnology期刊Guest Associate Editor
主持项目情况:
作为负责人，主持国家自然科学基金（4项）、国家重点研发计划课题、道达尔公司合作研发项目等十余项各类项目
国家自然科学基金面上项目，调控细胞形态以优化蓝细菌光合固碳效率的策略开发及生理影响研究，32270103，2023-2026
国家自然科学基金面上项目，基于ATP合成酶扰动策略的蓝细菌高温高光耐受性改造和机制研究，32070084，2021-2024
国家自然科学基金面上项目，基因组复制工程辅助的连续进化技术提高蓝细菌高pH耐受性的研究，31770092，2018-2021
国家自然科学基金青年基金项目，蓝细菌能量-还原力代谢重平衡新策略及其生理影响研究，31600034，2017-2019
法国道达尔集团企业委托研发项目，改造光合微生物以提升细胞生长速度、固碳能力以及中链烯烃的合成，2020-2021
洁净能源创新研究院合作基金，第二代微生物组生物光伏关键技术研究，29DNL202014, 2021-2023
代表性论著：
1. Zhang, S.#, Sun, J.#, Feng, D., Sun, H., Cui, J., Zeng, X., Wu, Y., Luan, G.*, Lu, X.*,(2023) Unlocking the potentials of cyanobacterial photosynthesis for directly converting carbon dioxide into glucose. Nature Communications,14, 3425.
2.Sun, H.#, Luan, G. *#, Ma, Y., Lou, W., Chen, R., Feng, D., Zhang, S., Sun, J., Lu, X.*, (2023) Engineered hypermutation adapts cyanobacterial photosynthesis to combined high light and high temperature stress. Nature Communications, 14, 1238.
3.Zhu, H., Xu, L, Luan, G., Zhan, T., Kang, Z., Li, C., Lu, X.*, Zhang, X.*, Zhu, Z.*, Zhang, Y.*, Li, Y.* (2022) A miniaturized bionic ocean-battery mimicking the structure of marine microbial ecosystems. Nature Communications, 13, 5608.
4.Luan, G., Lu, X.*, (2018) Tailoring cyanobacterial cell factory for improved industrial properties. Biotechnology Advances, 36(2):430-442.
5.Luan, G.*, Zhang, S., Wang, M., Lu, X.*, (2019) Progress and perspective on cyanobacteria glycogen metabolism engineering. Biotechnology Advances, 37(5):771-786; IF2022=17.68.
6.Luan, G., Cai, Z.*, Gong, F., Dong, H., Lin, Z., Zhang, Y. and Li, Y.*, (2013) Developing controllable hypermutable Clostridium cells through manipulating its methyl-directed mismatch repair system. Protein & Cell, 4, 854-8623.
7.Luan, G.#, Zhang#, S., Lu, X.*, (2019) Engineering cyanobacteria chassis cells toward more efficient photosynthesis. Current Opinion in Biotechnology, 62:1-6.
8.Luan, G., Cai, Z.*, Li, Y.* and Ma, Y., (2013) Genome replication engineering assisted continuous evolution (GREACE) to improve microbial tolerance for biofuels production. Biotechnology for Biofuels, 6:137.
9.Luan, G.#, Qi, Y.#, Wang, M., Li, Z., Duan, Y., Tan, X., and Lu, X.*, (2015) Combinatory strategy for characterizing and understanding the ethanol synthesis pathway in cyanobacteria cell factories. Biotechnology for Biofuels, 8, 184.
10.Zhu, Z., Luan, G.*, Tan, X., Zhang, H., and Lu, X.*, (2017) Rescuing ethanol photosynthetic production of cyanobacteria in non-sterilized outdoor cultivations with a bicarbonate-based pH-rising strategy. Biotechnology for Biofuels, 10:93.
11.Zhang, M., Luo, Q., Sun, H., Fritze, J., Luan, G.*, Lu, X.*, (2022) Engineering a controllable targeted protein degradation system and a derived OR-GATE-Type inducible gene expression system in Synechococcus elongatus PCC 7942. ACS Synthetic Biology, 11:125-134. IF2022=5.25.
12.Luan, G.#, Bao, G.#, Lin, Z., Li, Y., Chen, Z., Li, Y., Cai, Z.*, (2015) Comparative genome analysis of a thermotolerant Escherichia coli obtained by Genome Replication Engineering Assisted Continuous Evolution (GREACE) and its parent strain provides new understanding of microbial heat tolerance. New Biotechnology, 32(6):732-738.
13. Luan, G.#, Dong, H.#, Zhang, T., Lin Z., Zhang, Y., Li, Y., Cai, Z.*, (2014) Engineering cellular robustness of microbes by introducing the GroESL chaperonins from extremophilic bacteria. Journal of Biotechnology, 178, 38-40.
14. Wang, M., Luan, G.*, Lu, X.*, (2019) Systematic identification of a neutral site on chromosome of Synechococcus sp. PCC7002, a promising photosynthetic chassis strain. Journal of Biotechnology, 295:37-40.
15. Wang, M., Luan, G.*, Lu, X.*, (2020) Engineering ethanol production in a marine cyanobacterium Synechococcus sp. PCC7002 through simultaneously removing glycogen synthesis genes and introducing ethanolgenic cassettes. Journal of Biotechnology, 317:1-4.
联系方式：
luangd@qibebt.ac.cn
