刘奕

酵母合成生物学方向

详细介绍:

2009.09-2015.01     中国科学院青岛生物能源与过程研究所,生物化学与分子生物学(硕博连读),理学博士

2015.09-2020.06     查尔姆斯理工大学,合成生物学,博士后

2022.10-至今          中国科学院青岛生物能源与过程研究所,项目研究员


已发表论文:

1. Yi Liu, Quanli Liu, Anastasia Krivoruchko, Sakda Khoomrung, and Jens Nielsen*. Engineering yeast phospholipid platform for de novo oleoylethanolamide production. Nat. Chem. Biol. 2020, 16:197-205.

2. Quanli Liu#, Yi Liu#, Gang Li, Otto Savolainen, Yun Chen, and Jens Nielsen*. De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories. Nat. Commun. 2021, 12(1):6085. (#Co-first author)

3. Yi Liu and Jens Nielsen*. Recent trends in metabolic engineering of microbial chemical factories. Curr. Opin. Biotechnol. 2019, 60: 188-197.

4. Yi Liu, Cong Wang, Jinyong Yan, Wei Zhang, Wenna Guan, Xuefeng Lu, and Shengying Li*. Hydrogen peroxide-independent production of α-alkenes by OleTJE P450 fatty acid decarboxylase. Biotechnol. Biofuels 2014, 7: 28-40.

5. Yi Liu, Jiangtao Qiao, Xianzheng Yuan, Rongbo Guo, and Yanling Qiu*. Hydrogenispora ethanolica gen. nov., sp. nov., an anaerobic carbohydrate-fermenting bacterium from anaerobic sludge. Int. J. Syst. Evol. Microbiol. 2014, 64:1756-1762.

6. Wei Zhang, Yi Liu, Jinyong Yan, Shaona Cao, Fali Bai, Ying Yang, Shaohua Huang, Lishan Yao, Yojiro Anzai, Fumio Kato, Larissa M. Podust, David H. Sherman* and Shengying Li*. New reactions and products resulting from alternative interactions between the P450 enzyme and redox partners. J. Am. Chem. Soc. 2014, 136: 3640-3646.

7. Quanli Liu, Yi Liu, Yun Chen, and Jens Nielsen*. Current state of aromatics production using yeast: achievements and challenges. Curr. Opin. Biotechnol. 2020, 65:65-74.

8. Jinyong Yan*, Yi Liu, Cong Wang, Bingnan Han and Shengying Li*. Assembly of a lipase and a P450 fatty acid decarboxylase to constitute a novel biosynthetic pathway for production of 1-alkenes from renewable triacylglycerols and oils. Biotechnol. Biofuels 2015, 8: 34-43.

9. Bo Fang, Huifang Xu, Yi Liu, Fengxia Qi, Wei Zhang, Hui Chen, Cong Wang, Yilin Wang, Wenxia Yang and Shengying Li*. Mutagenesis and redox partners analysis of the P450 fatty acid decarboxylase OleTJE. Sci. Rep. 2017, 7:44258.

10. Wei Zhang, J. L. Fortman, Jacob C. Carlson, Jinyong Yan, Yi Liu, Fali Bai, Wenna Guan, Junyong Jia, Teatulohi Matainaho, David H. Sherman*, and Shengying Li*. Characterization of the bafilomycin biosynthetic gene cluster from Streptomyces lohii. Chembiochem. 2013,14(3): 301-306.

11. Dongying Liu, Yi Liu, Xuehui Men, Qunqun Guo, Rongbo Guo, Yanling Qiu*. Isolation and characterization of Thermopirellula anaerolimosa gen. nov., sp. nov., an obligate anaerobic hydrogen-producing bacterium of the phylum Planctomycetes. Acta Microbiol. Sin. 2012, 52(8): 994-1001.

12. Rui Pereira, Olena Ishchuk, Xiaowei Li, Quanli Liu, Yi Liu, Maximillian Otto, Yun Chen, Verena Siewers, and Jens Nielsen. Metabolic Engineering of Yeast. In Metabolic Engineering: Concepts and Applications (Volume 13a, eds Nielsen J, Stephanopoulos G, Lee S) 689-733 (WILEY-VCH GmbH, Weinheim, 2021).


联系方式:

liuyi@qibebt.ac.cn



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